• 姓名: 饶伟
  • 性别: 女
  • 职称: 研究员
  • 职务: 
  • 学历: 
  • 电话: 
  • 传真: 
  • 电子邮件: 
  • 通讯地址: 北京市海淀区中关村东路29号
    简  历:
  • 2006/5-2009/7            中国科学院理化技术研究所,制冷及低温工程,博士

                                        研究论文:基于碱金属的肿瘤微创消融方法研究

    2003/9-2006/1            哈尔滨工业大学,供热,供燃气,通风及制冷工程,硕士                                                                     

                                       研究论文:变片距换热器在空气源热泵应用的数值分析

    1999/9-2003/7            哈尔滨工业大学,建筑环境与设备工程,学士      

     

    2011/11-       美国俄亥俄州立大学,生物医学工程系,博士后 (Post-doctoral researcher)

     

    2010/7-2011/9     美国弗吉尼亚联邦大学,药物化学系,研究助理Research scientist )

     

    2009/7-2010/4           中国科学院理化技术研究所,低温生物与医学实验室,助理教授(Assistant professor)

     

     

    社会任职:
  • 2013-          w 会员, American Society of Mechanical Engineers (ASME)

    2013-          w 会员, American Biomedical Engineering Society (BMES)

     

    研究方向:
  • w 肿瘤干细胞靶向冷冻消融

    w 温敏性纳米药物控释系统与热疗结合的肿瘤复合治疗

    w 基于纳米技术的干细胞冷冻保存

    w 干细胞生物仿生系统

    承担科研项目情况:
  • ACS fund                      w A combined cancer treatment of cryoablation and nanoparticle drug delivery

    NIH fund                       w Microencapsulation of oocytes for low-cpa (cryoprotectant) vitrification

    NSF fund                      w Quantification of the biotransport phenomena in low-cryoprotectant (CPA) vitrification of living cells

    NSFC fund               w 基于血管介入式加热的恶性肿瘤全身热疗方法研究

    NSFC fund                    w 基于微纳米材料的计算机辅助适形化射频热疗方法研究

    代表论著:
  • 1.    Huang H., Choi, J.K., Rao, W., Zhao, S., Agarwal, P., Zhao G. and He X. Alginate hydrogel microencapsulation inhibits devitrification and enables large-volume low-CPA cell vitrification. Advanced Functional Materials. 2015, 25(44): 6839-6850. (IF: 11.805)

    2.    Rao, W., Huang, H., Wang, H., Zhao, S., Dumbleton, J., Zhao, G., and He, X. Nanoparticle-mediated intracellular delivery enables cryopreservation of human adipose-derived stem cells using trehalose as the sole cryoprotectant. ACS Applied Materials & Interfaces. 2015, 7(8): 5017–5028. (IF: 6.723)

    3.    Rao, W.*, Wang, H.*, Han, J., Zhao, S., Dumbleton, J., Agarwal, P., Zhang, W., Zhao, G., Yu, J., Zynger, D.L., Lu, X., and He, X. Chitosan-decorated doxorubicin-encapsulated nanoparticle targets and eliminates tumor reinitiating cancer stem-like cells. ACS Nano. 2015; 9(6):5725-5740. (*equal contribution) (IF: 12.881)

    4.    Rao, W.*, Wang, H. *, Zhong, A. *, Yu, J., Lu, X., and He, X. Nanodrug-mediated thermotherapy of cancer stem-like cells. Journal of Nanoscience and Nanotechnology. 2015, 15:1-9.(*: Equal contribution) (IF: 1.556)

    5.    Zhao, S., Agarwal, P., Rao, W., Huang, H., Zhang, R., Liu, Z., Yu, J., Weisleder, N., Zhang, W., and He, X. Coaxial electrospray of liquid core-hydrogel shell microcapsules for encapsulation and miniaturized 3D culture of pluripotent stem cells. Integrative Biology. 2014,6(9): 874-884. (IF: 3.765)

    6.    Rao, W.*, Zhao, S.*, Yu, J., Lu, X., Zynger, D.L., and He, X. Enhanced enrichment of prostate cancer stem-like cells with miniaturized 3D culture in liquid core-hydrogel shell microcapsules. Biomaterials. 2014, 35(27): 7762-7773. (*: Equal contribution) (IF: 8.557)

    7.    Rao, W., Bellotti, A., Littrup, P.J., Yu, J., Lu, X., and He, X. Nanoparticle-encapsulated doxorubicin enhances cryoablation of cancer stem-like cells. Technology. 2014, 2(1): 28-35.

    8.    Rao, W., Zhang, W., Poventud-Fuentes, I., Wang, Y., Lei, Y., Weekes, B., Li, C., Lu, X., Yu, J., and He, X. Thermally responsive nanocapsule-encapsulated curcumin and its combination with mild hyperthermia for enhanced cancer cell destruction. Acta Biomaterialia. 2014,10(2): 831-842. (IF: 6.025)

    论著

    1.     刘静,饶伟得巍. 低成本医.北京, 科技出版社. 2010.

    2.   He X., Rao W., and Wang H. Book Chapter: “Polymeric Nanoparticles for Cryobiological Applications” edited by Xiaoming He and John C Bischof, in book Multiscale Technologies for Cryomedicine, World Scientific Publishing Co. 2015.

     专利

    1.    He X., Rao, W. Method for encapsulation of hydrophilic molecules using nanoparticles. Tech ID #T2015-130. (Accepted for Assessment). 申请日期:20141217

    2.    He X., Rao, W. Chitosan decorated on nanoparticles for targeted drug delivery to cancer stem-like cells. Tech ID #T2015-115. (Accepted for Assessment). 申请日期:2014124.

    3.    刘静,饶伟. 冷热探针治疗系统. 类型:中国发明专利. 公开号:CN101292897 A, 申请号: 200710098735.2. 申请日期:2007425.

    4.    刘静,邓中山,项士海,饶伟. 基于金属颗粒或其化合物热化学反应的肿瘤靶向热疗方法.类型:中国发明专利. 公开号:CN101219071 A,申请号:200710062601.5. 申请日期:2007111.

    获奖及荣誉:
  • 2009                      w 中国科学院理化技术研究所,三好学生标兵

    2008                      w 中国科学院理化技术研究所,所长奖学金,两次

    2007/2008             w 中国科学院理化技术研究所,优秀研究生

    2002                      w 中海特别奖学金, 学年排名第一  (GPA:3.97, 1/256)

    2000-2003             w 哈尔滨工业大学,一等奖学金,三次 (5%)