1999.09 – 2002.08: 理学硕士,华东理工大学
2002.09 – 2006.10: 理学博士,德国美因茨大学
2006.10 – 2007.4:德国马普高分子研究所博士后
2007.5 – 2010.1:德国马普高分子研究所,课题组长
2010.2 – 2023.5:中科院化学所研究员、博士生导师
2023.5 –至今:中科院理化技术研究所研究员、博士生导师
通过研究自然界中抗冻生物体内的抗冻机制,揭示冰晶成核与生长的分子机制,并指导可控冰晶成核及生长的控冰材料的创制,以控冰材料替代传统冻存中毒性成分的使用,并开展其在冷冻保存细胞、组织和器官中的应用研究。
(2) 防覆冰界面材料
研究冰在固体表面生长的分子机制,设计开发超低冰黏附界面材料,解决低温、高湿环境下风电机组、电力输送、极地舰船等的防覆冰问题。
(3) 冷冻组装调控分子聚集
利用冷冻组装策略,精确调控分子组装过程,实现对有机纳米颗粒及多尺度结构功能材料的可控制备;并应用于介观尺度可控有机纳米光催化、生物组织的高分辨成像、骨/韧带等组织工程等领域。
|
项目名称 |
经费来源 |
经费/万元 |
项目年限 |
目前状态 |
担任角色 |
1 |
组织器官仿生控冰冻存的分子机制 |
基金委重大项目 |
1489.2万 |
2023-2027 |
在研 |
主持 |
2 |
高分子材料表面 与界面的研究 |
基金委杰出青年科学基金 |
400万 |
2020-2024 |
在研 |
主持 |
3 |
防冰新材料调控冰晶 形成的关键物理化学 问题研究 |
基金委重点项目 |
301万 |
2018-2022 |
结题 |
主持 |
4 |
神经元前体细胞及眼角膜内皮组织控冰冷冻 保存材料 |
中科院重点部署项目 |
400万 |
2021-2025 |
在研 |
主持 |
5 |
仿生控冰冷冻保存 试剂研究 |
中科院0-1原始创新项目 |
300万 |
2019-2024 |
在研 |
主持 |
6 |
睾丸组织生精小管冻融损伤机理与功能修复 |
科技部国家重点研发计划 |
431万 |
2022-2025 |
在研 |
主持 |
2. Janus effect of antifreeze proteins on ice nucleation; Liu K., Wang C. *, Ma J., Shi G., Yao X., Fang H., Song Y., Wang J. * PNAS 2016, 51,14739.
3. Distinct ice patterns on solid surfaces with various wettabilities; Liu J., Zhu C., Liu K., Jiang Y., Song Y., Francisco J *., Zeng X. *, Wang J.*, PNAS, 2017, 114, 11285. (highlighted by Nature)
4. Bioinspired Ice-Binding Materials for Tissue and Organ Cryopreservation; Liu Z.; Zheng, X.; Wang, J. *, J. Am. Chem. Soc. 2022, 144, 5685.
5. Tuning ice nucleation with counterions on polyelectrolyte brush surfaces; He Z. *, Xie W. *, Liu Z., Liu G., Wang Z., Gao Y., Wang J., Science-Advances, 2016, 2, e160034.
6. Graphene Oxide Restricts Growth and Recrystallization of Ice Crystals;Geng H., Liu X., Shi G. *, Bai G., Ma J., Chen J., Wu Z., Song Y., Fang H., Wang J. *, Angewandte Chemie-International Edition, 2017, 56, 997.
7. Spontaneous Freezing of Water between 233 and 235 K Is Not Due to Homogeneous Nucleation; Han Xue,Yang Fu,Youhua Lu,Dezhao Hao,Kaiyong Li,Guoying Bai,Zhong-Can Ou-Yang, Jianjun Wang *,and Xin Zhou *,Journal of the American Chemical Society, 2021, 143, 13548.
8. Use of Ion Exchange To Regulate the Heterogeneous Ice Nucleation Efficiency of Mica; Shenglin Jin+ , Yuan Liu+, Malte Deiseroth+, Jie Liu, Ellen H. G. Backus, Hui Li, Han Xue, Lishan Zhao, Xiao Cheng Zeng *, Mischa Bonn *, and Jianjun Wang *, Journal of the American Chemical Society, 2020. 142, 17956.
9. Precise Control Over Kinetics of Molecular Assembly: Production of Particles with Tunable Sizes and Crystalline Forms; Qingrui Fan, Linhai Li , Han Xue , Heng Zhou, Lishan Zhao, Jie Liu, Junqiang Mao, Shuwang Wu, Shizhong Zhang, Chenyang Wu, Xueming Li, Xin Zhou *, and Jianjun Wang * Angew Chem Int Ed Engl,2020, 59, 15141.
10. Highly efficient solar anti-icing/deicing via a hierarchical structured surface; Chenyang Wu, Hongya Geng, Sicong Tan, Jianyong Lv, Haiqiao Wang *, Zhiyuan He *,Jianjun Wang, Materials Horizons, 2020, 7, 2097.
11. A Freezing-Induced Turn-On Imaging Modality for Real-Time Monitoring of Cancer Cells in Cryosurgery; Zhiyuan He, Pai Liu, Shizhong Zhang, Jie Yan, Mengni Wang, Zhengxu Cai *and Jianjun Wang *, Angewandte Chemie-International Edition, 2019, 58, 3834.
12. Heterogeneous ice nucleation correlates with bulk-like interfacial water, Shuwang Wu,Jinger Zang,Shenglin Jin,Zuowei Wang,Jianping Wang,Yefeng Yao,Zhiyuan He *,and Jianjun Wang *, Science Advances, 2019, 5, 9825.
13. Bioinspired Materials for Controlling Ice Nucleation, Growth, and Recrystallization; He Zhiyuan, Liu, Kai, Wang, Jianjun *, Accounts of Chemical Research, 2018, 51, 1082.
14. Nonionic and Water-Soluble Poly(D/L?serine) as a Promising Biomedical Polymer for Cryopreservation. Yuling Sun *, Jie Liu, Zhibo Li, Jianjun Wang *, and Yanbin Huang *, ACS Appl. Mater. Interfaces. 2021, 13, 18461.
15. All-Day Anti-icing/Deicing Film based on Combined Photo-Electro-Thermal Conversion, Tongtong Hao;Zhicheng Zhu;Huige Yang *, Zhiyuan He *, Jianjun Wang *, ACS Appl. Mater. Interfaces, 2021, 13, 44948.
16. Bioinspired L?Proline Oligomers for the Cryopreservation of Oocytes via Controlling Ice Growth; Qingyuan Qin , Lishan Zhao, Zhang Liu, Tao Liu, Jiangxue Qu, Xiaowei Zhang, Rong Li, Liying Yan, Jie Yan *, Shenglin Jin *, Jianjun Wang *, and Jie Qiao, ACS Applied Materials & Interfaces, 2020, 12, 18352.
17. Fabrication of Anti-Icing Surfaces by Short alpha-Helical Peptides; Zhang Yifan, Liu Kai, Li Kaiyong, Gutowski Voytek, Yin Yuan, Wang Jianjun *, ACS Applied Materials & Interfaces, 2018, 10, 1957.
18. Competing Effects between Condensation and Self-Removal of Water Droplets Determine Antifrosting Performance of Superhydrophobic Surfaces; Guanlei Zhao, Guisheng Zou, Wengan Wang, Ruikun Geng, Xiao Yan, Zhiyuan He, Lei Liu *, Xin Zhou, Jainyong Lv *, Jianjun Wang *, ACS Applied Materials & Interfaces, 2020, 12, 7805.
19. Bioinspired Crowding Inhibits Explosive Ice Growth in Antifreeze Protein Solutions; Zhang Liu, Yan Wang, Xia Zheng, Shenglin Jin, Shuo Liu, Zhiyuan He, Jun-Feng Xiang, Jianjun Wang *, Biomacromolecules, 2021, 22, 2614.
20. Ion-Specific Effects on the Growth of Single Ice Crystals; Shizhong Zhang, Chuanbiao Zhang, Shuwang Wu, Xin Zhou, Zhiyuan He *, and Jianjun Wang *, The Journal of Physical Chemistry Letters, 2021, 12, 8726.
主要授权中国发明及PCT专利:
(1) 王健君;金晟琳;严杰;乔杰;闫丽盈;李蓉;一种筛选控冰材料的方法;中国发明专利,ZL201910282418.9。
(2) 王健君;金晟琳;严杰;乔杰;闫丽盈;李蓉;一种控冰材料的分子设计方法;中国发明专利,ZL201910282422.5。
(3) 王健君;金晟琳;严杰;乔杰;闫丽盈;李蓉;一种氨基酸类冷冻保存液及其制备方法;中国发明专利,ZL202010172548.X。
(4) 王健君;金晟琳;严杰;乔杰;闫丽盈;李蓉;一种冷冻保存液及其制备方法;中国发明专利,ZL202010172544.1。
(5) 王健君;金晟琳;严杰;乔杰;闫丽盈;李蓉;一种无DMSO的冷冻保存液及其制备方法;中国发明专利,ZL202010171866.4。
(6) 王健君;金晟琳;严杰;乔杰;闫丽盈;李蓉;一种肽类化合物和含有该化合物的冷冻保存液;中国发明专利,ZL202010171868.3。
(7) 王健君;金晟琳;严杰;乔杰;闫丽盈;李蓉;一种冷冻保存用解冻液及解冻方法;中国发明专利,ZL201910282421.0。
(8) WANG, Jianjun; JIN, Shenglin;LV, Jianyong, YAN, Jie;QIAO, Jie;YAN, Liying;LI, Rong;一种仿生控冰材料及含有该仿生控冰材料的冷冻保存液;PCT发明专利,俄罗斯国家阶段申请2021123840/05(049923)。
2016年获化学科学奖教金(创新奖)
人才队伍